Safety and effectiveness of superselective embolization of the uterine arteries in the treatment of uterine fibroids
10.3760/cma.j.cn341190-20221009-00784
- VernacularTitle:超选择性子宫动脉栓塞治疗子宫肌瘤安全性及有效性分析
- Author:
Tao ZHOU
1
;
Jiwen CHEN
;
Xinmiao LI
;
Feng GU
;
Lijia WANG
Author Information
1. 浙江省荣军医院放射介入科，嘉兴 314000
- Keywords:
Uterus;
Leiomyoma;
Arterial embolization;
Surgery;
Estradiol;
Luteinizing hormone;
Follicle stimulating hormone;
Progesterone;
Safety;
Treatment results
- From:
Chinese Journal of Primary Medicine and Pharmacy
2023;30(3):379-383
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To analyze the safety and effectiveness of superselective embolization of the uterine arteries in the treatment of uterine fibroids.Methods:The clinical data of 60 patients with uterine fibroids who were admitted to Zhejiang Veteran Hospital from February 2020 to February 2022 were retrospectively analyzed. These patients were divided into a control group and an observation group ( n = 30/group) according to different surgical methods. The control group underwent conventional surgery. The observation group underwent superselective embolization of the uterine arteries. Uterine size, uterine fibroid size, postoperative hormone level, and complications were compared between the two groups. Results:There was no significant difference in total response rate between the observation and control groups [93.33 (28/30) vs. 83.33 (25/30), χ2 = 1.46, P > 0.05]. After surgery, serum estradiol, luteinizing hormone, follicle-stimulating hormone, and progesterone levels in the observation group were (164.14 ± 19.97) ng/L, (2.43 ± 1.47) IU/L, (2.51 ± 1.14) IU/L, and (5.05 ± 0.43) μg/L, respectively, which were significantly lower than (190.23 ± 21.62) ng/L, (3.78 ± 1.63) IU/L, (3.94 ± 1.23) IU/L, (8.22 ± 1.35) μg/L in the control group ( t = 4.86, 3.37, 4.67, 12.25, all P < 0.05). The incidence of postoperative complications in the observation group was significantly lower than that in the control group [3.33% (1/30) vs. 20.00% (6/30), χ2 = 4.04, P < 0.05). Conclusion:Compared with conventional surgery, superselective embolization of the uterine arteries is more effective on uterine fibroids, better keep postoperative hormone level stable, and reduce or avoid short- and long-term complications. Therefore, superselective embolization of the uterine arteries for the treatment of uterine fibroids deserves the clinical promotion.
