Value of Gd-EOB-DTPA-enhanced MRI for prediction of the pathological grade and early recurrence rate of hepatocellular carcinoma
10.3760/cma.j.cn341190-20210901-01020
- VernacularTitle:钆塞酸二钠MRI增强成像预测肝细胞癌病理分级及早期复发率的价值分析
- Author:
Junyang HUANG
1
;
Yanyi HUANG
;
Kaoye LUO
;
Junke YANG
Author Information
1. 百色市人民医院放射科，百色 533000
- Keywords:
Carcinoma,hepatocellular;
Magnetic resonance imaging;
Pathology;
Recurrence;
Neoplasm grading;
Disodium gadolinium selenate
- From:
Chinese Journal of Primary Medicine and Pharmacy
2023;30(2):265-269
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the value of gadolinium ethoxybenzyl diethylenetriaminepentaacetic acid (Gd-EOB-DTPA)-enhanced MRI in predicting the pathological grade and early recurrence rate of hepatocellular carcinoma.Methods:The imaging data, pathological data, and follow-up data of 90 patients with hepatocellular carcinoma who underwent Gd-EOB-DTPA-enhanced MRI examination and surgical treatment in People's Hospital of Baise from January 2016 to October 2017 were retrospectively analyzed. The correlation between the signal intensity of contrast-enhanced MRI and postoperative pathological grade was analyzed. Kaplan-Meier survival analysis was performed to investigate the effects of the signal characteristics of hepatobiliary lesions on the early recurrence rate of hepatocellular carcinoma.Results:A total of 59 (65.56%) patients showed low-intensity signals and 31 (34.44%) patients showed mixed-intensity signals. High-intensity signal was not found in any patients. The signal intensity of the hepatobiliary phase was significantly correlated with the pathological grade of the tumor ( χ2 = 2.26, P = 0.040) and tumor size ( t = 3.10, P = 0.033). The early recurrence rate of hepatocellular carcinoma was significantly higher in patients exhibiting mixed-intensity signals than that in patients exhibiting low-intensity signals ( χ2 = 2.25, P = 0.041). Conclusion:Gd-EOB-DTPA-enhanced MRI in the hepatobiliary phase with different signal intensities has the potential to predict the pathological grade and early recurrence rate of hepatocellular carcinoma.
