Different enteral nutrition methods combined with swallowing rehabilitation training for Alzheimer's disease complicated by dysphagia
10.3760/cma.j.cn341190-20211215-01388
- VernacularTitle:不同肠内营养方法联合吞咽康复训练治疗阿尔茨海默病伴吞咽障碍的效果比较
- Author:
Jianliang HUANG
1
;
Xiaolu DU
Author Information
1. 金华市第二医院老年内科，金华 321000
- Keywords:
Alzheimer disease;
Deglutition disorders;
Enteral nutrition;
Swallowing rehabilitation training;
Nasogastric tube;
Naso-intestinal tube;
Body mass index
- From:
Chinese Journal of Primary Medicine and Pharmacy
2023;30(1):97-101
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the clinical efficacy of different enteral nutrition methods combined with swallowing rehabilitation training in the treatment of Alzheimer's disease complicated by dysphagia.Methods:A total of 120 patients with Alzheimer's disease and dysphagia who received treatment in the Department of Geriatric Medicine, the Second Hospital of Jinhua from October 2019 to March 2021 were included in this study. They were randomly and evenly divided into four groups: A, B, C, and D. Patients in groups A, B, C, and D were given nasogastric tube feeding, naso-intestinal tube feeding, nasogastric tube feeding + swallowing rehabilitation training, and naso-intestinal tube feeding + swallowing rehabilitation training, respectively. After 12 weeks of treatment, total response rate, nutritional status, and complications were compared between the four groups.Results:After 12 weeks of treatment, total response rate in group D was the highest (100.0%), which was significantly higher than that in the other three groups (group A: 13.3%; group B: 40.0%; group C: 73.3%; χ2 = 45.88, 25.71, 9.23, all P < 0.05). After treatment, the nutritional status [body mass index (BMI): (21.42 ± 1.85) kg/m 2, (23.17 ± 2.03) kg/m 2] and patient satisfaction (60.0%, 100.0%) in groups C and D were significantly superior to those in group A [BMI: (19.01 ± 1.72) kg/m 2; patient satisfaction: 10.0%) and group B [BMI: (19.86 ± 1.69) kg/m 2; patient satisfaction: 33.3%]. Group D had the best nutritional status ( t = 7.01, 5.14, 1.78, all P < 0.05) and the highest patient satisfaction ( χ2 = 49.09, 30.00, 15.00, all P < 0.001). Conclusion:Naso-intestinal tube feeding combined with swallowing rehabilitation training is the best treatment for Alzheimer's disease complicated by dysphagia among the studied enteral nutrition feeding methods and therefore deserves clinical promotion.
