Development status of vector-mediated Eg95 vaccine of Echinococcus granulosus
10.3760/cma.j.cn231583-20220226-00046
- VernacularTitle:载体介导的细粒棘球绦虫Eg95疫苗的研制现状
- Author:
Wengui LI
1
;
Yatang CHEN
Author Information
1. 重庆医科大学附属第一医院传染病寄生虫病研究所，重庆 400016
- Keywords:
Echinococcus granulosus;
Eg95 protein;
Vaccine
- From:
Chinese Journal of Endemiology
2023;42(8):684-688
- CountryChina
- Language:Chinese
-
Abstract:
Cystic echinococcosis (CE), caused by the larva of Echinococcus granulosus (Eg), is one of the key parasitic diseases to prevent and control in China. The Eg95 protein is a recognized vaccine candidate molecule, and the development of vector-mediated Eg95 vaccine is one of the current research hotspots in CE. This article summarizes the development status of Eg95 vaccine such as vaccinia virus, orf virus, goatpox virus, rabies virus, Salmonella typhimurium, Bacille Calmette-Guerin, Agrobacterium tumefaciens and Bifidobacteria bifidum, in order to provide valuable information for the immune prevention of CE.
