Research progress of the relationship between fluorosis and cardiovascular disease
10.3760/cma.j.cn231583-20220601-00195
- VernacularTitle:氟中毒与心血管系统疾病关系的研究进展
- Author:
Yiming ZHAO
1
;
Weiwei LIU
;
Yanshu LI
;
Yuting JIANG
;
Mingman ZU
;
Ruru YANG
;
Bingyun LI
Author Information
1. 哈尔滨医科大学中国疾病预防控制中心地方病控制中心，哈尔滨 150081
- Keywords:
Fluorosis;
Cardiovascular system;
Oxidative stress;
Lipid metabolism;
Epigenetics
- From:
Chinese Journal of Endemiology
2023;42(7):598-602
- CountryChina
- Language:Chinese
-
Abstract:
Fluorosis is widely prevalent worldwide, and China is one of the countries with a high incidence of endemic fluorosis. In recent years, study on non skeletal damage caused by fluorosis, especially cardiovascular system damage, has gradually increased. Fluoride can cause cardio vascular arteriosclerosis, hypertension and other diseases, while cardiovascular disease have hidden and acute onset, and the mortality rate has increased year by year in recent years. At present, the mechanism of cardiovascular diseases caused by fluoride is not yet clear, and further clarification is needed. This article provides an overview of the effects of fluoride on cardiovascular diseases from three aspect: epidemiological investigation, animals experiment, and in vitro cell experiment. It categorizes and analyzes the pathogenesis, providing new ideas for the study of cardiovascular system damage caused by fluorosis.
