Research progress on the role of macrophages in echinococcosis and the regulation of macrophages by parasite-derived molecules
10.3760/cma.j.cn231583-20211122-00383
- VernacularTitle:巨噬细胞在棘球蚴病中的作用及虫源性分子对巨噬细胞调控的研究进展
- Author:
Ning YANG
1
;
Renyong LIN
Author Information
1. 新疆医科大学第一附属医院临床医学研究院 省部共建中亚高发病成因与防治国家重点实验室,乌鲁木齐 830011
- Keywords:
Echinococcosis;
Macrophages;
Immunoregulation
- From:
Chinese Journal of Endemiology
2023;42(3):246-251
- CountryChina
- Language:Chinese
-
Abstract:
As a major member of innate immunity, macrophage can eliminate pathogens through cell phagocytosis, antigen presentation and immune regulation, and play an important role in parasitic infections such as Echinococcus. Echinococcus can regulate the function of host macrophages through a variety of parasite-derived molecules, such as protein and nucleic acid molecules, and realize long-term parasitism in the host. This article focuses on the research progress of the role of macrophages in echinococcosis and the regulation of macrophages by parasite-derived molecules.