Characteristics and artemisinin based treatment effect of 362 malaria cases in the peacekeeping mission area of the Democratic Republic of the Congo
10.3760/cma.j.cn231583-20211010-00343
- VernacularTitle:刚果（金）维和任务区362例疟疾病例的发病特征及基于青蒿素的治疗效果
- Author:
Xuan WANG
1
;
Fei AN
;
Pengjiang ZHANG
;
Jianying SHANGGUAN
;
Yaozhu PAN
Author Information
1. 联勤保障部队第940医院内分泌科，兰州 730050
- Keywords:
Malaria;
Compound dihydroartemisinin;
Peacekeeping;
Africa;
The Democratic Republic of the Congo
- From:
Chinese Journal of Endemiology
2022;41(11):924-928
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To analyze the epidemiological characteristics, diagnosis and treatment of malaria in the peacekeeping mission area of the Democratic Republic of the Congo (DRC), and to evaluate the efficacy of artemisinin based combination therapy (ACT), to provide clinical basis for the diagnosis and treatment of malaria.Methods:The clinical data of malaria-infected peacekeepers admitted to the Chinese Secondary Hospital of the United Nations Stabilization Mission in DRC (MONUSCO) from January 2014 to September 2020 were collected, and the general information, incidence characteristics, treatment and clinical outcomes of the patients were retrospectively analyzed.Results:From January 2014 to September 2020, 362 peacekeepers were hospitalized with malaria, the average annual incidence case was 54 cases per year, and the annual incidence was 9.5/1 000, with a median of 2.5 days (1 - 9 days) from onset to diagnosis. Severe malaria accounted for 7.73% (28/362) and uncomplicated malaria accounted for 92.27% (334/362). The incidence rate was 37.57% (136/362) in the dry season (April to September) and 62.43% (226/362) in the rainy season (October to March of the following year). After ACT antimalarial treatment, all patients were cured clinically. Eight cases recurred and were cured clinically after drug conversion ACT retreatment.Conclusions:In the peacekeeping mission area of DRC, peacekeepers are generally susceptible to malaria. ACT has a high cure rate, safety and efficiency in clinical treatment.
