Hemodynamic Pathogenesis of AVM.
- Author:
Sei Young LEE
1
;
Bum Tae KIM
;
Soo Bin IM
;
Sun Chul HWANG
;
Won Han SHIN
Author Information
1. Department of Neurosurgery, Soonchunhyang University Hospital, Bucheon, Korea. bumtkim@sch.ac.kr
- Publication Type:Original Article
- Keywords:
Adaptive autoregulatory displacement;
AVM hemodynamics
- MeSH:
Aneurysm;
Arterial Pressure;
Cerebral Hemorrhage;
Hemodynamics*;
Hemorrhage;
Humans;
Hypotension;
Neurons;
Paralysis;
Perfusion;
Vasodilation
- From:Korean Journal of Cerebrovascular Surgery
2004;6(1):11-15
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Significantly decreased perfusion pressure is common in vascular territories irrigating neuronal tissue in patients with AVMs. There is evidence that "adaptive autoregulatory displacement" occurs in these patients which maintains cerebral blood flow above ischemic levels. Chronic arteriolar vasodilatation does not usually lead to vasomotor paralysis because most patients maintain a constant cerebral blood flow in spite of increased systemic arterial pressure. AVM hemodynamics appears to play an important role in the etiology of spontaneous intracerebral hemorrhage. Large AVM with high-flow and severe arterial hypotension are least likely to hemorrhage. In patients with AVMassociated aneurysm, the etiology of these dual lesions is likely multifactorial, with hemodynamic stresses having a dominant influence.