Meta analysis of the efficacy of three kinds of uterine barriers in preventing re-adhesion after separation of moderate or severe intrauterine adhesion
10.3760/cma.j.cn115455-20220530-00511
- VernacularTitle:三种宫腔屏障预防中重度宫腔粘连分离术后再粘连疗效的Meta分析
- Author:
Lifang WANG
1
;
Xiaoyu LI
;
Yuhuan LIU
;
Yanzhong ZHAO
Author Information
1. 首都医科大学附属复兴医院妇产科，北京 100038
- Keywords:
Uterine adhesion;
COOK balloon;
Foley balloon;
Intrauterine device;
Meta analysis
- From:
Chinese Journal of Postgraduates of Medicine
2023;46(1):57-63
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To evaluate the efficacy of three kinds of uterine barriers: cook balloon, Foley balloon and intrauterine devices in preventing re-adhesion after separation of moderate or severe intrauterine adhesions.Methods:Seven databases including PubMed, Embase, Medline, Cochrane Library, China HowNet, Wanfang and CQVIP were used to retrieve, and the randomized controlled trials on the effect of using COOK balloon, Foley balloon and intrauterine devices to prevent re-adhesion after the separation of moderate and severe intrauterine adhesions were collected from the establishment of the database to December 2021. Revman 5.1 software was used for Meta analysis.Results:A total of 16 articles were selected according to the inclusion criteria. Meta analysis results showed that the rates of preventing postoperative re-adhesion, improving menstruation and pregnancy in COOK balloon were significantly better than those in intrauterine devices ( OR = 0.31, 2.75 and 1.58; 95% CI 0.19 to 0.49, 1.74 to 4.35 and 1.07 to 2.34; P<0.01); the rates of preventing postoperative re-adhesion, improving menstruation and pregnancy in Foley balloon were significantly better than those in intrauterine devices ( OR = 0.39, 1.90 and 1.73; 95% CI 0.27 to 0.57, 1.33 to 2.71 and 1.02 to 2.39; P<0.01 or <0.05). Conclusions:The use of COOK balloon and Foley balloon to prevent adhesion is better than the use of intrauterine devices in preventing re-adhesion in patients with moderate or severe intrauterine adhesions.
