CT portal vein imaging combined with liver function indexes to predict the risk of bleeding from gastric fundus esophageal varices in liver cirrhosis
10.3760/cma.j.cn115455-20220113-00035
- VernacularTitle:CT门静脉成像联合肝功能指标对肝硬化胃底食管静脉曲张出血风险的预测
- Author:
Meng LI
1
;
Yaming CHEN
;
Benhao ZHAO
;
Bo HU
;
Yan HU
Author Information
1. 皖北煤电集团总医院放射科，宿州 234000
- Keywords:
Liver cirrhosis;
Esophageal and gastric varices;
Hemorrhage;
Liver function tests;
CT portal vein imaging
- From:
Chinese Journal of Postgraduates of Medicine
2022;45(12):1101-1104
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the value of CT portal vein imaging combined with liver function indexes in predicting the risk of esophageal variceal bleeding in patients with liver cirrhosis.Methods:A total of 82 patients with liver cirrhosis complicated with gastric fundus esophageal varices in Wanbei Coal-Electricity Group General Hospital were selected and divided into bleeding group (24 cases) and non-bleeding group (58 cases) according to the occurrence of gastric fundus esophageal varices bleeding within 6 weeks after admission. General data of the two groups, CT portal vein imaging parameters at admission including diameter of main portal vein (MPV), diameter of splenic vein (SPV), diameter of left gastric vein (LGV), serum liver function indexes including alanine aminotransferase (ALT), aspartate aminotransferase (AST), total bilirubin (TBIL) levels were compared between the two groups, and analyzed the value of CT portal vein imaging parameters and serum liver function indexes levels in predicting the risk of gastric fundus esophageal varices bleeding.Results:The age and diameter of MPV, SPV, LGV in bleeding group were higher than those in the non-bleeding group: (55.17 ± 12.02) years vs. (53.71 ± 10.48) years, (18.05 ± 2.74) mm vs. (15.22 ± 2.18) mm, (13.68 ± 1.35) mm vs. (12.26 ± 1.43) mm, (6.82 ± 1.38) mm vs. (5.30 ± 0.94) mm; the levels of serum ALT, AST, TBIL in bleeding group were lower than those in the non-bleeding group: (23.71 ± 5.74) U/L vs. (34.95 ± 8.26) U/L, (27.65 ± 6.61) U/L vs. (39.29 ± 10.24) U/L, (17.20 ± 5.49) U/L vs. (26.13 ± 7.85) U/L, there were statistical differences ( P<0.05). The results of receiver operating characteristic curve showed that the area under the curve (AUC) of combined index to predict gastric fundus esophageal varices bleeding was 0.889 (95% CI 0.812-0.967), and the sensitivity and specificity were 83.34% and 81.03%, respectively. Conclusions:CT portal vein imaging combined with liver function indexes has a good value in predicting the risk of gastric fundus esophageal varices bleeding in liver cirrhosis.
