Progress in diagnosis and treatment of retinal vasoproliferative tumor
10.3760/cma.j.cn115989-20200712-00488
- VernacularTitle:视网膜血管增生性肿瘤的诊疗进展
- Author:
Gongpeng SUN
1
;
Changzheng CHEN
Author Information
1. 武汉大学人民医院眼科中心,武汉 430060
- Keywords:
Retinal neoplasms;
Retinal vasoproliferative tumor;
Diagnosis;
Treatment;
Clinical manifestation
- From:
Chinese Journal of Experimental Ophthalmology
2023;41(7):693-696
- CountryChina
- Language:Chinese
-
Abstract:
Retinal vasoproliferative tumor (RVPT) is a rare benign glial proliferative tumor of unknown origin.The fundus is typically characterized by yellow or pink tumor-like lesions of the retina around the inferior temporal region, often accompanied by subretinal fluid, exudation, epiretinal membrane and other complications.Typical RVPT showed high fluorescence on fundus fluorescein angiography, diffuse leakage in venous phase and late stage, uneven middle or high reflection signal on B-ultrasound, and it was not difficult to diagnose combined with fundus changes.Atypical RVPT should be differentiated from retinal capillary hemangioma caused by von Hippel-Lindau disease, Coats disease and familial exudative vitreoretinopathy.The pathogenesis of RVPT is unclear, but histopathology shows that it may be the reactive proliferation of glial cells.At present, there is no unified treatment plan for RVPT, mainly cryotherapy, laser photocoagulation, local radiotherapy, transpupillary thermal therapy or photodynamic therapy for tumor.For patients with vitreous hemorrhage, vitreoretinal surgery is feasible.This article reviewed the clinical features, diagnosis and differential diagnosis, pathology and pathogenesis, and treatment progress of RVPT.