Pulmonary Edema following Phenylephrine Intranasal Spray Administration during the Induction of General Anesthesia in a Child.
10.3349/ymj.2005.46.2.305
- Author:
Ji Seon SON
1
;
Sang Kyi LEE
Author Information
1. Department of Anesthesiology and Pain Medicine, Research Institute of Clinical Medicine, Chonbuk National University Medical School and Hospital, Jeonju, Korea. sjs6803@hanmail.net
- Publication Type:Case Report
- Keywords:
Phenylephrine;
beta-adrenergic antagonist;
pulmonary edema
- MeSH:
Administration, Intranasal;
Adolescent;
*Anesthesia, General;
Dentigerous Cyst/surgery;
Humans;
Male;
Phenylephrine/*adverse effects;
Pulmonary Edema/*chemically induced/radiography;
Radiography, Thoracic
- From:Yonsei Medical Journal
2005;46(2):305-308
- CountryRepublic of Korea
- Language:English
-
Abstract:
Topical phenylephrine, an agent used to facilitate nasotracheal intubation and prevent nasal mucosal bleeding, can cause severe hypertension in some patients, secondary to its stimulation of alpha-adrenergic receptors. Moreover, a high incidence of pulmonary edema is found in patients whose phenylephrine administration is followed by treatment with beta-blocking agents. We report a case of acute pulmonary edema in a pediatric patient who developed severe hypertension after the inadvertent administration of a large dose of topical nasal phenylephrine, followed by beta-adrenergic antagonists (esmolol).
