Current Status of Standardization of Inhalant Allergen Extracts in Korea.
10.4168/aair.2014.6.3.196
- Author:
Kyoung Yong JEONG
1
;
Jae Hyun LEE
;
Eun Jin KIM
;
Joo Shil LEE
;
Sang Heon CHO
;
Soo Jong HONG
;
Jung Won PARK
Author Information
1. Department of Internal Medicine and Institute of Allergy, Yonsei University College of Medicine, Seoul, Korea. parkjw@yuhs.ac
- Publication Type:Review
- Keywords:
Allergen;
allergen extract;
standardization
- MeSH:
Allergens;
Amino Acid Sequence;
Centers for Disease Control and Prevention (U.S.);
Cockroaches;
Diagnosis;
Hypersensitivity;
Immunotherapy;
Korea;
Pollen;
Pyroglyphidae
- From:Allergy, Asthma & Immunology Research
2014;6(3):196-200
- CountryRepublic of Korea
- Language:English
-
Abstract:
Allergy diagnosis and immunotherapy in Korea rely mostly on imported allergen extracts. However, some allergens that are not important in Western countries are not commercially available, and even the same species of allergen source often displays differences in allergenicity due to amino acid sequence polymorphisms. Therefore, it is essential to prepare allergen extracts that reflect regional characteristics. Allergen standardization has been performed since 2009 with the support of the Korea Center for Disease Control and Prevention. Here, we summarize the current status of allergen standardization, focusing on the house dust mite and cockroach. Pollen allergens that are under investigation are also briefly described.
