Risk factors of extrauterine growth retardation in very preterm infants with birth weight less than 1 500 g
10.3760/cma.j.issn.2096-2932.2023.03.003
- VernacularTitle:出生体重<1 500 g极早产儿宫外发育迟缓危险因素分析
- Author:
Qi WU
1
;
Yiming ZHU
;
Xiaofan SUN
;
Ailing SU
;
Yi ZHENG
;
Junjie LU
Author Information
1. 南京市妇幼保健院，南京医科大学附属妇产医院儿科，南京 210011
- Keywords:
Very preterm infants;
Extrauterine growth retardation;
Risk factors
- From:Chinese Journal of Neonatology
2023;38(3):141-145
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To study the risk factors of extrauterine growth retardation (EUGR) during hospitalization in very preterm infants (VPIs) with birth weight (BW) <1 500 g.Methods:From Jan 2015 to Dec 2020, clinical data of VPIs admitted to neonatal department our hospital were retrospectively studied. The infants were assigned into EUGR group and non-EUGR group according to their weight at discharge. Multivariate logistic regression analysis was used to analyze the risk factors of EUGR in VPIs.Results:A total of 969 VPIs were enrolled, including 400 cases of EUGR (41.3%). Multivariate logistic regression analysis showed that Z-score of BW ( OR=0.057, 95% CI 0.037-0.088, P<0.001) was closely correlated with the occurrence of EUGR and growth velocity (GV) after regain BW ( OR=0.537, 95% CI 0.479-0.602, P<0.001) was a protective factor for EUGR. Maternal hypertension during pregnancy ( OR=1.895, 95% CI 1.059-3.394, P=0.031), asphyxia at birth ( OR=2.508, 95% CI 1.265-3.347, P=0.004) and moderate to severe bronchopulmonary dysplasia (BPD) ( OR=2.660, 95% CI 1.503-4.708, P=0.001) were risk factors for EUGR at discharge. Conclusions:EUGR is still common in VPIs. Increased GV after regain BW, prevention and treatment of moderate to severe BPD may reduce the incidence of EUGR at discharge in VPIs.
