Clinical research advance in immunotherapy of pancreatic cancer
10.3760/cma.j.cn115610-20230407-00158
- VernacularTitle:胰腺癌免疫治疗临床研究进展
- Author:
Botao CHEN
1
;
Xianhai MAO
Author Information
1. 湖南省人民医院（湖南师范大学附属第一医院）肝胆外科，长沙 410005
- Keywords:
Pancreatic neoplasms;
Immunotherapy;
Tumor microenvironment;
Immune checkpoint inhibitors;
CD40;
Tumor vaccine;
Oncolytic virus;
Adoptive cell therapy
- From:
Chinese Journal of Digestive Surgery
2023;22(5):610-615
- CountryChina
- Language:Chinese
-
Abstract:
Pancreatic cancer is one of the most common tumors in digestive system, which is characterized by insidious clinical symptoms, strong invasion, easy metastasis and high mortality. In recent years, immunotherapy is a new direction to the treatment of solid tumors, but its applica-tion in pancreatic cancer is limited by tumor microenvironment of pancreatic cancer. The authors systematically analyze the tumor microenvironment of pancreatic cancer, summarize the clinical researches related to pancreatic cancer immunotherapy, and discuss the prospect of pancreatic cancer immunotherapy.
