Drug Rash With Eosinophilia and Systemic Symptoms Syndrome Induced by Chloral Hydrate in Early Childhood.
10.4168/aair.2014.6.3.270
- Author:
Suk Dong YOO
1
;
Su Gon KIM
;
Seong Heon KIM
;
Hye Young KIM
Author Information
1. Department of Pediatrics, Medical Research Institute of Pusan National University Hospital, Pusan National University School of Medicine, Busan, Korea. pearlhy@naver.com
- Publication Type:Case Report
- Keywords:
Drug hypersensitivity;
chloral hydrate
- MeSH:
Allopurinol;
Anticonvulsants;
Chloral Hydrate*;
Drug Hypersensitivity;
Drug Hypersensitivity Syndrome;
Eosinophilia*;
Exanthema*;
Female;
Fever;
Humans;
Hypersensitivity;
Infant;
Lymphatic Diseases;
Sulfonamides
- From:Allergy, Asthma & Immunology Research
2014;6(3):270-272
- CountryRepublic of Korea
- Language:English
-
Abstract:
Drug rash with eosinophilia and systemic symptoms (DRESS) syndrome, also known as drug-induced hypersensitivity syndrome (DIHS), is a rare, acute and severe life-threatening systemic disease. DRESS syndrome is characterized by fever, lymphadenopathy, rash, hypereosinophilia and involvement of systemic organs. The most commonly implicated drugs are anticonvulsants, sulfonamides and allopurinol. Chloral hydrate is a sedative and hypnotic drug frequently used in pediatric patients. We first report a case of DRESS syndrome induced by chloral hydrate in a 14-month-old female.
