Discussion on hot issues in liver transplantation for hepatocellular carcinoma
10.3760/cma.j.cn115610-20230118-00025
- VernacularTitle:肝癌肝移植热点问题探讨
- Author:
Yarong GUO
1
,
2
;
Jun XU
;
Hezhao ZHANG
;
Zhiyong SHI
;
Yan WANG
Author Information
1. 山西医科大学第一医院肿瘤科,太原
2. 030001
- Keywords:
Liver neoplasms;
Liver transplantation;
Down-staging treatment;
Bridging therapy;
Immunosuppressant;
Recurrence
- From:
Chinese Journal of Digestive Surgery
2023;22(2):209-213
- CountryChina
- Language:Chinese
-
Abstract:
Liver diseases are common in China and the incidence and mortality of primary liver cancer are among the top in the world. As one of the therapeutic methods for hepatocellular carcinoma (HCC), liver transplantation has become an important technique in hepatic surgery. Most of patients with HCC have progressed to stage B or C of Barcelona Clinic Liver Cancer staging when diagnosed. How to reduce the dropout rate of HCC patients due to the progression of tumor when waiting for liver transplantation, develop individualized immunosuppressant plans for HCC patients after liver transplantation, and accurately manage patients with HCC recurrence after liver transplan-tation are the current hotspots of research. The authors review the relevant literature, summarize the treatment experience, and discuss the hot issues in liver transplantation for HCC, in order to provide reference for related treatment.