The role and application of organ reserve capacity in sepsis

VernacularTitle:器官储备功能在脓毒症中的作用及应用
Author: Jingyao ZHANG ¹ ; Rui CHEN ; Yingmu TONG ; Qi XIN ; Chang LIU
Author Information

1. 西安交通大学第一附属医院外科重症医学科，西安　710061
Keywords: Sepsis; General surgery; Organ reserve capacity; Monitoring and asse-ssment; Treatment
From: Chinese Journal of Digestive Surgery 2022;21(12):1518-1523
CountryChina
Language:Chinese
Abstract: Sepsis is a life-threatening organ dysfunction caused by a dysregulated host response to infection. The injured organ is the main target of treatment. Organic functional reserve refers to the ability of an organ or system to return to its original physiological state following acute physiological stress or pathological injury, which has not received widespread attention. The organ reserve capacity is expected to complement the existing sepsis-related scoring system to optimize disease severity grading and evaluate prognosis. Source control, appropriate using of antibiotics and organ supporting can reduce further damage of organ reserve capacity, while nutritional therapy and rehabilitation may enhance it. Therefore, the authors believe that in further basic theoretical research and clinical practice, more attention can be paid to the monitoring and management of organ reserve capacity in sepsis, which may help improving the diagnosis and treatment of sepsis and prognosis of patients.