Advances on diagnosis of sepsis-associated encephalopathy in children
10.3760/cma.j.issn.1673-4912.2023.06.012
- VernacularTitle:儿童脓毒症相关性脑病的诊断方法研究进展
- Author:
Xiaoxuan QI
1
;
Chunfeng LIU
Author Information
1. 中国医科大学附属盛京医院儿科，沈阳 110004
- Keywords:
Sepsis associated encephalopathy;
Sepsis;
Diagnosis;
Sepsis associated brain dysfunction;
Quantitative electroencephalography
- From:
Chinese Pediatric Emergency Medicine
2023;30(6):461-465
- CountryChina
- Language:Chinese
-
Abstract:
Sepsis-associated encephalopathy(SAE) is a diffuse brain dysfunction caused by sepsis.The main clinical manifestations are abnormal mental state, high mortality and poor prognosis.At present, there is no unified diagnostic standard for SAE.The exclusion diagnosis is mainly based on clinical symptoms and signs, combined with laboratory examination and imaging auxiliary examination.Among them, brain magnetic resonance imaging and quantitative electroencephalography can early detect brain dysfunction and predict the prognosis of children, which play an important role in the early diagnosis and prognosis assessment of SAE.Cerebral oxygen monitoring can dynamically reflect the changes of brain function and can be used for long-term monitoring of children with severe brain function injury.SAE is closely associated with poor prognosis, and mortality will increase with the extention of hospitalization.Therefore, early identification of SAE is of great significance to reduce mortality.
