Current status of metabolomics in pediatric community-acquired pneumonia

VernacularTitle:代谢组学在儿童社区获得性肺炎的研究现状
Author: Shuqiong LIU ¹ ; Tian YU ; Saizhen ZENG ; Lingling CHEN ; Pei WU ; Qian HUANG
Author Information

1. 湖南师范大学附属第一医院（湖南省人民医院）儿童医学中心，长沙　410005
Keywords: Community-acquired pneumonia; Metabolomics; Children
From: Chinese Pediatric Emergency Medicine 2023;30(2):126-130
CountryChina
Language:Chinese
Abstract: Community-acquired pneumonia(CAP) is one of the leading causes of death in children under 5 years of age.Early identification and clarification of its severity and appropriate therapeutic measures can improve survival, but there are limitations in the existing laboratory indices applied to diagnose CAP.Therefore, it is still necessary to find new and highly specific biomarkers that can identify the etiology and predict the severity of the disease before it worsens in children, and provides a basis for more effective therapeutic measures.Metabolomics provides a new way to search for biomarkers and pathogenesis through qualitative and quantitative analysis of metabolite changes in biological samples.This review summarized the latest research progress on metabolomics in childhood CAP, hoping to provide ideas for the early diagnosis and treatment of childhood CAP.