Gut-lung axis: The crosstalk between gut microbiota and lung
10.3760/cma.j.issn.1673-4912.2023.02.005
- VernacularTitle:肠肺轴——谁影响谁
- Author:
Yuan GOU
1
;
Wenjian WANG
Author Information
1. 深圳市儿童医院呼吸科 518038
- Keywords:
Gut-lung axis;
Gut microbiota;
Respiratory tract microecology;
Probiotics
- From:
Chinese Pediatric Emergency Medicine
2023;30(2):104-109
- CountryChina
- Language:Chinese
-
Abstract:
Human gut is a huge microbial habitat.Gut microbiota provides nutrition for human body, regulates metabolism and intestinal epithelial development, and induces innate immunity, and has significant impacts on growth, development and aging.Gut microbiota is influenced by genetics, living environment or life pattern, diseases and other factors, and also interacts with organs of the whole body through various of ways.The lung and the large intestine have embryological homology, common mucosal immune system, secretory function and other modern biological basis.Gut microbiota not only regulates the function of the gastrointestinal tract, but also affects the health and disease of the respiratory system, forming the " gut-lung axis". Intestinal microecological mediation and regulation based on the theory of gut-lung axis has achieved beneficial effects on the prevention and treatment of respiratory tract infection, asthma, and other respiratory diseases.
