Intestinal microbiota and pediatric inflammatory bowel disease
10.3760/cma.j.issn.1673-4912.2023.02.004
- VernacularTitle:肠道微生态与儿童炎症性肠病
- Author:
Qianru JIA
1
;
Zhiqin MAO
Author Information
1. 中国医科大学附属盛京医院儿内科，沈阳 110004
- Keywords:
Children;
Inflammatory bowel disease;
Intestinal microbiota;
Probiotic
- From:
Chinese Pediatric Emergency Medicine
2023;30(2):98-103
- CountryChina
- Language:Chinese
-
Abstract:
Inflammatory bowel disease is a chronic recurrent inflammatory disease of the intestine of unknown origin.It is currently thought to be mediated by a combination of susceptibility genes, intestinal microecology and immune involvement, with all three interacting and influencing each other.This leads to a disruption of the intestinal microenvironment, which affects the host′s immune tolerance, and ultimately induces intestinal inflammation.In this review, we summarized the mechanisms of intestinal microbiota in children with inflammatory bowel disease and discussed new ideas of microecological agents for individualized treatment of children with inflammatory bowel disease.
