Robotic Mechanical Localization of Prostate Cancer Correlates with Magnetic Resonance Imaging Scans.
10.3349/ymj.2013.54.4.907
- Author:
Tae Young SHIN
1
;
Yeong Jin KIM
;
Sey Kiat LIM
;
Jung KIM
;
Koon Ho RHA
Author Information
1. Department of Urology, Urological Science Institute, Yonsei University College of Medicine, Seoul, Korea. khrha@yuhs.ac
- Publication Type:Original Article ; Evaluation Studies ; Research Support, Non-U.S. Gov't
- Keywords:
Prostate cancer;
diagnosis;
elasticity;
robotics;
MRI scans
- MeSH:
Aged;
Biopsy/methods;
Humans;
Magnetic Resonance Imaging/methods;
Male;
Middle Aged;
Predictive Value of Tests;
Prostatectomy;
Prostatic Neoplasms/*diagnosis/pathology/surgery;
Robotics/instrumentation/*methods;
Sensitivity and Specificity
- From:Yonsei Medical Journal
2013;54(4):907-911
- CountryRepublic of Korea
- Language:English
-
Abstract:
PURPOSE: To evaluate the concordance of cancer location of the tissue mapping from a mechanical pressure transducer with magnetic resonance imaging (MRI) scans. MATERIALS AND METHODS: A total of 60 indentations were performed on 5 prostate specimens obtained after radical prostatectomy utilizing a robotic indentation system. The mechanical elastic moduli of suspected malignant lesions were calculated and mapped, and their locations were compared with suspicious areas of malignancy on MRI scans. RESULTS: The concordance rate between the location mapping from the robotic indentation system and MRI scans results was 90.0% (54/60). The sensitivity and specificity of the robotic indentation system were 87.9% (29/33) and 92.6% (25/27), respectively. The positive predictive value and negative predictive value were 93.5% (29/31) and 93.1% (27/29), respectively. CONCLUSION: The locations of malignant lesions derived from our robotic indentation system correlated strongly with the locations of suspected areas of malignancy on MRI scans. Our robotic system may provide a more targeted biopsy of the prostate than conventional non-targeted systemic biopsy, possibly improving the diagnostic accuracy of prostatic biopsies for cancer.
