Biomarkers of gastrointestinal dysfunction in children
10.3760/cma.j.issn.1673-4912.2022.12.003
- VernacularTitle:儿童胃肠道功能障碍生物学标志物
- Author:
Fan YIN
1
;
Botao NING
Author Information
1. 上海交通大学医学院附属上海儿童医学中心重症医学科 200127
- Keywords:
Children;
Gastrointestinal dysfunction;
Inflammatory indicators;
Intestinal epithelial barrier damage markers;
Immunological markers;
Gut microbiome
- From:
Chinese Pediatric Emergency Medicine
2022;29(12):951-956
- CountryChina
- Language:Chinese
-
Abstract:
Due to incomplete function of gastrointestinal barrier, children are more likely to develop gastrointestinal dysfunction.The clinical application of related biomarkers helps early diagnosis and treatment of gastrointestinal dysfunction in children.By sorting out the studies in recent years, we explored the relationship between inflammatory indicators, intestinal epithelial barrier damage biomarkers, immunological biomarkers, gut microbiome and gastrointestinal dysfunction, and summarized the main problems and solutions faced in the research, which may help the screening, identification and clinical application of relevant biomarkers in subsequent research.
