Tracheal Wall Thickening Is Associated with the Granulation Tissue Formation Around Silicone Stents in Patients with Post-Tuberculosis Tracheal Stenosis.
10.3349/ymj.2013.54.4.949
- Author:
Jung Seop EOM
1
;
Hojoong KIM
;
Kyeongman JEON
;
Sang Won UM
;
Won Jung KOH
;
Gee Young SUH
;
Man Pyo CHUNG
;
O Jung KWON
Author Information
1. Division of Pulmonary and Critical Care Medicine, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea. hjk3425@skku.edu
- Publication Type:Original Article ; Observational Study
- Keywords:
Trachea;
tuberculosis;
stenosis;
bronchoscopy;
intervention;
stents
- MeSH:
Adult;
Bronchoscopy/methods;
Female;
Granulation Tissue/*pathology;
Humans;
Male;
Middle Aged;
Retrospective Studies;
Risk Factors;
Silicones;
Stents/*adverse effects;
Tomography, X-Ray Computed;
Trachea/*pathology;
Tracheal Stenosis/etiology/*pathology;
Tuberculosis/*complications
- From:Yonsei Medical Journal
2013;54(4):949-956
- CountryRepublic of Korea
- Language:English
-
Abstract:
PURPOSE: Tracheal restenosis due to excessive granulation tissue around a silicone stent requires repeated bronchoscopic interventions in patients with post-tuberculosis tracheal stenosis (PTTS). The current study was conducted to identify the risk factors for granulation tissue formation after silicone stenting in PTTS patients. MATERIALS AND METHODS: A retrospective study was conducted between January 1998 and December 2010. Forty-two PTTS patients with silicone stenting were selected. Clinical and radiological variables were retrospectively collected and analyzed. RESULTS: Tracheal restenosis due to granulation tissue formation were found in 20 patients (47.6%), and repeated bronchoscopic interventions were conducted. In multivariate analysis, tracheal wall thickness, measured on axial computed tomography scan, was independently associated with granulation tissue formation after silicone stenting. Furthermore, the degree of tracheal wall thickness was well correlated with the degree of granulation tissue formation. CONCLUSION: Tracheal wall thickening was associated with granulation tissue formation around silicone stents in patients with post-tuberculosis tracheal stenosis.
