Status quo and influencing factors of medication compliance in young newly diagnosed pulmonary tuberculosis patients
10.3760/cma.j.cn211501-20220527-01666
- VernacularTitle:青年初治肺结核患者服药依从性及其影响因素研究
- Author:
Yu JIANG
1
;
Jing YANG
;
Qian WU
;
Abulaiti GULISUMUHAN
;
Li SHI
;
Abulaiti XIADIYA
;
Meixin WANG
Author Information
1. 新疆医科大学护理学院,乌鲁木齐 830011
- Keywords:
Tuberculosis, pulmonary;
Youth;
Medication adherence;
Influencing factors
- From:
Chinese Journal of Practical Nursing
2023;39(18):1388-1395
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the medication adherence and its influencing factors in young newly diagnosed pulmonary tuberculosis patients during different treatment periods, in order to provide a theoretical basis for formulating precise medication management strategies and thus improving the treatment success rate.Methods:A cross-sectional survey was conducted using a stratified random sampling method to select 283 young newly diagnosed pulmonary tuberculosis patients who visited and registered in the Kashgar region of Xinjiang from September 2021 to February 2022. The patients were divided into three groups according to the treatment time of receiving standard chemotherapy regimen: A (1-2 months of medication), B (3-4 months of medication), and C (5-6 months of medication), with 77, 89, and 117 cases, respectively. The clinical data of tuberculosis patients were collected by using the general information questionnaire,Eight-Item Morisky Medication Adherence Scale and Tuberculosis Medication Adherence Scale for tuberculosis patients.Results:Those who take medication well of three groups of young newly treated pulmonary tuberculosis patients were 93.5% (72/77), 89.9% (80/89), and 82.1% (96/117), respectively. The difference among the three groups was statistically significant ( χ2=6.23, P<0.05). Logistic regression analysis showed that social support was an influential factor for the 1st to 2nd month of medication ( OR=0.536, P<0.05); treatment confidence and psychological status were influential factors for the 3rd to 4th month of medication ( OR=0.668, 2.212, both P<0.05); comorbidity, social support, psychological status, and coping style were influential factors for the 5th to 6th month of medication ( OR values were 0.428 - 9.518, all P<0.05). Conclusions:The relevant factors that affect medication adherence vary among young newly diagnosed pulmonary tuberculosis patients at different stages of treatment. Accurate medication management strategies should be developed based on the influencing factors at each stage.