Nursing care of 5 children on Blinatumomab therapy with relapsed refractory acute B lymphocyte leukemia
10.3760/cma.j.cn211501-20221118-03541
- VernacularTitle:复发难治急性B淋巴细胞白血病儿童行贝林妥欧单抗治疗的护理5例
- Author:
Junxia WANG
1
;
Jinyuan HOU
;
Miaomiao YANG
;
Huimin ZHANG
Author Information
1. 中国医学科学院血液病医院（中国医学科学院血液学研究所）实验血液学国家重点实验室 国家血液系统疾病临床医学研究中心 细胞生态海河实验室 天津医学健康研究院，天津 301600
- Keywords:
Leukemia;
Pediatric;
Nursing care;
Blinatumomab
- From:
Chinese Journal of Practical Nursing
2023;39(17):1346-1349
- CountryChina
- Language:Chinese
-
Abstract:
To summarize the experience of 5 children with relapsed and refractory acute B lymphocyte leukemia treated with Blinatumomab, during the whole nursing processes, careful nursing was carried out before, during and after infusion. The key points of nursing include: reasonable cooperation with nursing staff and specialized training, design a condition observation form, timely grasp changes in the condition, early identify adverse reactions such as cytokine storms, neurotoxicity, and allergies, and ensure the safety of the children. Through personnel, articles and personalized liquid preparation table, ensure accurate dose, smooth infusion and save hospital expenses ￥3, 846~201, 910 for children. Payattention to the psychological burden of children and their families and attach importance to psychological care. Follow the psychological burden of children and caregivers, and pay attention to psychological nursing. As the results, 3 chidlren successfully completed the first cycle of Blinatumomab. But 2 chidlren interrupted due to the tumor burden. Follow up for 5-12 months showed that 2 cases survived, 1 case died of progressive disease after discharge, and 2 cases died of transplant complications.
