Progress in surgical treatment of infantile spasms
10.3760/cma.j.cn101070-20220612-00702
- VernacularTitle:婴儿痉挛症的外科治疗进展
- Author:
Hua WANG
1
;
Luxi RAN
Author Information
1. 中国医科大学附属盛京医院小儿神经内科,沈阳 110004
- Keywords:
Infantile spasms;
Treatment;
Surgical treatment;
Indication;
Preoperative evaluation
- From:
Chinese Journal of Applied Clinical Pediatrics
2023;38(2):111-115
- CountryChina
- Language:Chinese
-
Abstract:
Infantile spasms(IS) is the prevalent epilepsy syndrome in infancy, characterized by an early age of onset, distinctive seizure type, hypsarrhythmia on electroencephalography, and psychomotor retardation.Despite the fact that medication therapy is the primary treatment for IS, there are still some children with IS who are resistant to drug therapy, which is extremely detrimental to their prognosis.Therefore, surgical therapy has increasingly become one of the most prominent IS treatments.As of now, the indications, preoperative evaluation, and surgical techniques of surgery are continuously being investigated based on variables such as the disease, etiology, age, etcetera.The effect of surgery on cognitive function, physical function, linguistic capacity, and memory function is gaining increasing interest.This article described the indications, preoperative evaluation, surgical procedures (including resection, palliative surgery, and stereotactic surgery), and postoperative efficacy of surgical treatment for IS, with the goal of improving the prognosis of IS through precise surgical treatment, and providing more treatment options and a good long-term prognosis for children with drug-resistant IS.