Research progress of respiratory virus infection associated acute necrotizing encephalopathy
10.3760/cma.j.cn101070-20230106-00008
- VernacularTitle:呼吸道病毒致急性坏死性脑病研究进展
- Author:
Jiehua CHEN
1
;
Yuejie ZHENG
;
Yanxia HE
;
Kunling SHEN
Author Information
1. 深圳市儿童医院呼吸科，深圳 518038
- Keywords:
Influenza virus;
Severe acute respiratory syndrome coronavirus 2;
Acute necrotizing encephalopathy;
Child
- From:
Chinese Journal of Applied Clinical Pediatrics
2023;38(1):10-16
- CountryChina
- Language:Chinese
-
Abstract:
Acute necrotizing encephalopathy (ANE) is a subtype of acute encephalopathy presented with disturbance of consciousness and symmetric bilateral thalamic necrosis in neuroradiology.Patients with ANE had a high mortality or severe neurological sequela.ANE usually secondary to virus infectious disease, in which influenza is a common etiology.During the 3 years of the worldwide pandemic of severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)infection, ANE has become a severe complication and cause of death in children, which has aroused much concern.Here is a review of the research progress of epidemiology, pathogenesis, diagnosis, treatments and prognosis of ANE, in order to improve the knowledge of clinicians on this disease.
