Metastatic risk assessment and related treatment progress of paraganglioma and pheochromocytoma

VernacularTitle:副神经节瘤和嗜铬细胞瘤的转移风险评估及相关治疗进展
Author: Jiaquan ZHOU ¹ ; Yushi ZHANG
Author Information

1. 海南省人民医院（海南医学院附属海南医院）泌尿外科，海口　570311
Keywords: Paraganglioma; Pheochromocytoma; Neuroendocrine tumor; Metastasis
From: Chinese Journal of Endocrine Surgery 2022;16(6):756-759
CountryChina
Language:Chinese
Abstract: Paraganglioma and pheochromocytoma (PPGL) is an uncommon neuroendocrine tumor with variable metastatic potential which is related to multiple factors, and has a clear genetic background. Metastatic PPGL requires systemic intervention after failure of surgical treatment, but the overall efficacy is poor. In this review, the related literatures were reviewed to describe PPGL from the histological origin and name evolution, genetic background and metastasis risk, metastasis risk prediction and prognosis assessment, challenges in the clinical staging and progress in the systemic treatment.