Evaluation index research of the randomized controlled trial of infertility treated by Traditional Chinese Medicine
10.3760/cma.j.cn115398-20210323-00282
- VernacularTitle:中医药治疗不孕症随机对照试验评价指标研究
- Author:
Jundong ZHANG
1
;
Jiangfeng LIU
;
Yisheng ZHANG
;
Xinyuan LIU
;
Qi CHENG
;
Shuo YANG
Author Information
1. 南京大学信息管理学院2022级博士研究生，南京 210023
- Keywords:
Infertility;
Assessment indicators;
Randomized controlled trial;
Traditional Chinese Medicine
- From:
International Journal of Traditional Chinese Medicine
2023;45(4):492-497
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To collect and analyze the evaluation index of infertility treated by Traditional Chinese Medicine (TCM), which will lay a foundation for the establishment of the core index and evaluation index system of TCM treating infertility.Methods:By retriving the published literatures of randomized controlled trials of infertility treated by TCM in the database of CNKI, VIP, Wanfang, SinoMed, PubMed and Cochrane Library from January 1, 2011 to December 31, 2020, and after the screening according to the creteria of inclusion and exclusion, this paper analyzed the normal indexes of infertility and the pathogenic indexes of TCM.Results:A total of 95 RCTs were included, including 9 069 patients aged between 20-39 years old. The average sample size of each RCT study was 95, involving 78 evaluation criteria. The highest frequency of use was the total effective rate, etiological-index analysis found that the general indicators of infertility such as the total effective rate, pregnancy rate, TCM syndrome scores,and common etiological factors such as LH, FSH are the characteristic indicators.Conclusion:There are many problems in the evaluation indexes of clinical trials of treating infertility by TCM, such as great differences in number and not standardized usage. It is necessary to carry out research on the construction of core indicator and evaluation indicator systems of infertility according to different etiologies.
