Clinical application and mechanism research progress of Wuling Powder in the treatment of brain edema
10.3760/cma.j.cn115398-20220104-00035
- VernacularTitle:五苓散治疗脑水肿临床应用及机制研究进展
- Author:
Han BO
1
;
Xiaoping ZHAO
;
Xiaoxuan FAN
;
Juan YU
;
Mengjie ZHANG
;
Wen SUN
Author Information
1. 陕西中医药大学2020级硕士研究生，咸阳 712000
- Keywords:
Wu Ling San;
Brain edema;
Action mechanism;
Clinical application;
Review
- From:
International Journal of Traditional Chinese Medicine
2023;45(2):243-247
- CountryChina
- Language:Chinese
-
Abstract:
Brain edema belongs to the category of "stroke" and "true headache", while Traditional Chinese Medicine mostly understands its core disease mechanisms from the perspectives of stasis, deficiency, and heat, and mostly treats the disease by using warming yang to induce diuresis and eliminating stasis to remove water. Wuling Powder has been lauded as the "first party to typhoid and relieving diuresis", which is used to cure clearing damp and promoting diuresis and warming yang and transforming qi, and has been clinically used in the treatment of brain edema caused by various causes such as head trauma, intracerebral hemorrhage, cerebral infarction, and intracranial space occupying, all with remarkable efficacy. Wuling Powder improves cellular energy supply, scavenges excess oxygen radicals and calcium ions in brain tissue, and reduces the damage to brain tissue caused by vascular inflammatory factors and regulates aquaporins and vascular endothelial growth factor, thereby achieving therapeutic effects.
