Analysis on the medication rules of Pu Ji Fang for treating acne externally based on data mining
10.3760/cma.j.cn115398-20210129-00298
- VernacularTitle:基于数据挖掘的《普济方》痤疮外治方用药特色研究
- Author:
Yisheng ZHANG
1
;
Jundong ZHANG
;
Xue LI
;
Xinyuan LIU
;
Jianan YANG
;
Zongyou LI
;
Ping SONG
Author Information
1. 中国中医科学院中医药信息研究所2020级博士研究生，北京 100700
- Keywords:
Data mining;
Pu Ji Fang;
Acne;
External treatment;
Medication rules;
The Ancient and Modern Medical Record Cloud Platform
- From:
International Journal of Traditional Chinese Medicine
2023;45(2):208-213
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To analyze the medication rules in the ancient book Pu Ji Fang for the external treatment of acne based on data mining method. Methods:By screening out the methods of treating acne externally in Pu Ji Fang and establishing a standardized medical record database, this paper adopted the web version of Ancient and Modern Medical Record Cloud Platform to calculate the frequency, properties, flavors, and meridians of those medicines, and conduct cluster analysis by using IBM SPSS Modeler 18.0 software to analyze the association rules. Results:A total of 87 prescriptions were selected, including 164 kinds of Chinese materia medica, among which. Radix Angelicae, Ligusticum Wallichii, Rhizoma Typhoni and lead powder are frequently appeared. The properties of those medicines are mainly warm, cold and mild; the flavors of those medicines are mainly spicy, acrid, sweet and bitter, and the meridians mainly belongs to lung, spleen, stomach and liver meridians. The medical pair and group with the strongest associationion are Ligusticum Wallichii- Radix Angelicae and Rhizoma Typhonii- Radix Angelicae- Ligusticum Wallichii. Those freuently appeared medicines could be grouped into three categories. The paste dosage that was frequently appeared has strong correlation with tallow, mercury and lead powder, while the powder dosage that was frequenctly appeared has strong correlation with Angelica Dahurica, Radix Saponicae, Gleditsia sinensis, Radices Ligustici Sinensis and Ligusticum Wallichii. Conclusions:The application of data mining method could preliminarily reveal the medication rules of Pu Ji Fang for the external treatment of acne. The main treatment method is XinSanFaYue. The three categories of Chinese materia medica are used to treat the syndrome of asthenic habitus attacked by exogenous pathogenic factors, exterior attacked by wind heat and hot blood stasis respectively, showing the rules of treating acne externally before Ming Dynasty and providing references for the clinical treatment of acne.
