Research progress of 4-nitroquinoline-1-oxide-induced esophageal squamous cell carcinoma model in mice
10.3760/cma.j.cn371439-20230227-00084
- VernacularTitle:4-硝基喹啉-1-氧化物诱导小鼠食管鳞状细胞癌模型的研究进展
- Author:
Jinge LI
1
;
Jing LI
;
Zhenhan ZHANG
;
Jianxin GUO
;
Jingpu WANG
;
Zhongbing WU
Author Information
1. 河北医科大学中西医结合学院，石家庄 050017
- Keywords:
4-nitroquinoline-1-oxide;
Esophageal squamous cell carcinoma;
In situ model
- From:
Journal of International Oncology
2023;50(7):437-441
- CountryChina
- Language:Chinese
-
Abstract:
Esophageal squamous cell carcinoma (ESCC) is one of the most common malignant tumors with a poor prognosis. 4-nitroquinoline-1-oxide (4NQO) is a water-soluble quinoline derivative that can successfully induce the production of squamous cell carcinoma in vivo. Establishing and optimizing experimental methods for 4NQO induced ESCC formation in mice can provide a more suitable in situ model for the study of ESCC.
