Mechanism of action of glucocorticoid receptors in the growth of hepatoma cells
10.3760/cma.j.cn371439-20230120-00047
- VernacularTitle:糖皮质激素受体在肝癌细胞生长中的作用机制
- Author:
Jiaxuan LI
1
;
Yinglu FENG
Author Information
1. 青岛大学医学部中西医结合中心，青岛 266071
- Keywords:
Receptors, glucocorticoid;
Liver neoplasms;
Glucocorticoids
- From:
Journal of International Oncology
2023;50(4):241-243
- CountryChina
- Language:Chinese
-
Abstract:
The glucocorticoid receptor (GR) plays a critical role in signal transduction, expression of related genes and apoptosis of cancer cells. Hepatocellular carcinoma is characterized by high aggressiveness and mortality. In the exploration of the relationship between GR and hepatocellular carcinoma, numerous studies have shown that GR has an inhibitory effect on the growth of hepatocellular carcinoma cells, which provides new ideas and methods for the clinical application of GR in the treatment of hepatocellular carcinoma.
