Research progress of CAR-T in the treatment of esophageal squamous cell carcinoma
10.3760/cma.j.cn371439-20221123-00045
- VernacularTitle:CAR-T在食管鳞状细胞癌治疗中的研究进展
- Author:
Hao DING
1
;
Jintao YING
;
Maoyong FU
Author Information
1. 川北医学院附属医院胸外科，南充 637000
- Keywords:
Esophageal squamous cell carcinoma;
Receptors, chimeric antigen;
Tumor microenvironment;
Immunotherapy
- From:
Journal of International Oncology
2023;50(4):231-235
- CountryChina
- Language:Chinese
-
Abstract:
Chimeric antigen receptor T cell (CAR-T) therapy, an emerging immunotherapy, has achieved remarkable results in the treatment of hematologic tumors. However, it's limited in the treatment of solid tumors such as esophageal squamous cell carcinoma due to various factors. Clarifying the reasons for the limitation of CAR-T therapy and exploring the corresponding solutions can provide new ideas and insights for the treatment of esophageal squamous cell carcinoma.
