Research progress on tumor microenvironment and immune combination therapy of MSS colorectal cancer
10.3760/cma.j.cn371439-20221213-00037
- VernacularTitle:MSS型结直肠癌肿瘤微环境及免疫联合治疗研究进展
- Author:
Liangfu XU
1
;
Yuanfei LI
Author Information
1. 山西医科大学第一临床医学院，太原 030001
- Keywords:
Colorectal neoplasms;
Tumor microenvironment;
Immunotherapy;
Microsatellite stable
- From:
Journal of International Oncology
2023;50(3):186-190
- CountryChina
- Language:Chinese
-
Abstract:
In recent years, immunotherapy, especially immune checkpoint inhibitors, has shown obvious advantages in prolonging the survival of patients with advanced tumors, and the tumor microenvironment is one of the important factors affecting the efficacy of immunity. Patients with microsatellite-stable colorectal cancer exhibit immune responses in combination with immune checkpoint inhibitor therapy. In-depth exploration of the tumor microenvironment characteristics of microsatellite-stable colorectal cancer and the application of combined immune checkpoint inhibitor therapy can provide new ideas and directions for colorectal cancer immunotherapy.
