Role of tertiary lymphoid structures in tumor immune microenvironment regulation and anti-tumor therapy
10.3760/cma.j.cn371439-20221121-00033
- VernacularTitle:三级淋巴结构在肿瘤免疫微环境调节和抗肿瘤治疗中的作用
- Author:
Mengqing CAO
1
;
Zhiyong XU
;
Yuting SHI
;
Kai WANG
Author Information
1. 浙江大学医学院附属第四医院呼吸与危重症医学科,义乌 322000
- Keywords:
Tertiary lymphoid structures;
Tumor microenvironment;
Treatment outcome
- From:
Journal of International Oncology
2023;50(3):169-173
- CountryChina
- Language:Chinese
-
Abstract:
Tertiary lymphoid structures (TLSs) is important channel for tumor immune cell infiltration. The existence of tumor TLSs is not only related to the prognosis of patients, but also to the efficacy of a variety of anti-tumor therapies. To explore the function and immunomodulatory mechanism of TLSs and its potential value as a tumor prognostic biomarker in comprehensive anti-tumor therapy will provide new ideas for follow-up research.