Research progress on the mechanism of bone marrow suppression after chemotherapy
10.3760/cma.j.cn371439-20221005-00006
- VernacularTitle:化疗后骨髓抑制机制的研究进展
- Author:
Qi SUN
1
;
Wenqian LI
;
Youbang XIE
;
Houfa ZHOU
Author Information
1. 青海大学研究生院，西宁 810016
- Keywords:
Hematopoietic stem cells;
Cellular senescence;
Myelosuppression;
Chemotherapy;
Hematopoietic microenvironment
- From:
Journal of International Oncology
2023;50(1):33-36
- CountryChina
- Language:Chinese
-
Abstract:
As an effective treatment for cancer, chemotherapy not only removes tumor cells, but also produces obvious killing effects on proliferating cells, especially hematopoietic cells, resulting in bone marrow suppression after chemotherapy, and affecting the effects of chemotherapy drug treatment and treatment cycle. Therefore, starting from the aspects of hematopoietic microenvironment damage and hematopoietic stem cell aging, to explore the mechanism of myelosuppression after chemotherapy, which provides new ideas and theoretical support for the intervention and management of bone marrow suppression after cancer chemotherapy.
