Research progress of ferroptosis in the treatment of leukemia
10.3760/cma.j.cn371439-20220623-00149
- VernacularTitle:铁死亡在白血病治疗中的研究进展
- Author:
Xinyu ZHOU
1
;
Xiuhong JIA
Author Information
1. 滨州医学院附属医院儿科，滨州 256603
- Keywords:
Leukemia;
Ferroptosis;
Therapeutics
- From:
Journal of International Oncology
2022;49(12):759-762
- CountryChina
- Language:Chinese
-
Abstract:
Leukemia is a group of hematologic malignancie. Ferroptosis is a novel of cell death caused by iron-dependent lipid peroxidation accumulation, which participates in the occurrence and development of leukemia. Activation of different regulatory sites in the ferroptosis pathway can promote the death of leukemia cells. Therefore, it can provide a new direction for the treatment of leukemia by inducing ferroptosis of cells.
