Risk factors and treatment progress of spontaneous rupture and hemorrhage in hepatocellular carcinoma
10.3760/cma.j.cn115396-20230312-00056
- VernacularTitle:肝细胞癌自发性破裂出血相关危险因素及治疗进展
- Author:
Gege CHENG
1
;
Shasha PENG
Author Information
1. 武汉科技大学医学院，武汉 430000
- Keywords:
Carcinoma, hepatocellular;
Rupture, spontaneous;
Risk factors;
Prognosis;
Treatment
- From:
International Journal of Surgery
2023;50(8):562-566
- CountryChina
- Language:Chinese
-
Abstract:
Hepatocellular carcinoma is one of the most common malignant tumors in clinical practice, and China has the highest incidence in the world. Spontaneous rupture of hepatocellular carcinoma is a serious complication of hepatocellular carcinoma. Its mechanism and risk factors are complex, including tumor size, location, hypertension, cirrhosis, HBsAg positivity, obesity and receiving targeted therapy with sorafenib, which may be its influencing factors. In recent years, the treatment methods of rupture and hemorrhage of hepatocellular carcinoma have been continuously improved and developed, including conservative treatment, transcatheter arterial chemoembolization, emergency hepatectomy, staged hepatectomy, etc.Transcatheter arterial chemoembolization followed by selective surgery is the most effective treatment at present. This article reviews the risk factors and treatment progress of rupture and hemorrhage of hepatocellular carcinoma, in order to provide reference for the direction of research on rupture and hemorrhage of hepatocellular carcinoma, so as to improve the prognosis and prolong the survival time of patients with early detection, early prevention and early treatment.
