New progress in the diagnosis and treatment of biliary tract tumors
10.3760/cma.j.cn115396-20230626-00182
- VernacularTitle:胆道肿瘤诊断与治疗的新进展
- Author:
Chaobo CHEN
1
;
Liang MAO
;
Yudong QIU
Author Information
1. 江苏省无锡市锡山人民医院普外科,无锡 214105
- Keywords:
Biliary tract neoplasms;
Surgical procedures, operative;
Diagnosis;
Adjuvant therapy;
Immunotherapy;
Comprehensive treatment
- From:
International Journal of Surgery
2023;50(8):545-551
- CountryChina
- Language:Chinese
-
Abstract:
Biliary tract cancers (BTC) is a type of digestive tract malignant tumors that originate from biliary epithelial cells, is characterized by strong occult and highly invasive, and has a high mortality rate. Early detection and diagnosis are considered to be the key to obtaining radical surgical treatment. R0 resection is an effective measure to benefit patients with BTC. However, most of the patients present with local progression or associated distant metastasis, making it impossible to undergo radical surgical treatment. With existing diagnosis and treatment methods, the 5-year survival rate of patients is still very low. Therefore, how to improve the level of diagnosis and treatment of BTC, prolong survival, and improve the quality of life has become an urgent problem to be solved. In view of the characteristics of BTC and the continuous deepening of clinical pathological molecular research, adjuvant therapy, precisely targeted therapy, immunotherapy, and comprehensive treatment are currently considered to be standardized diagnosis and treatment models and research directions beyond surgery. Therefore, this article systematically analyzes the current research progress of BTC both domestically and internationally, aiming to provide strategies for the diagnosis and treatment of patients with BTC.