Historical evolution of pancreatic fistula definition and current grading limitations and potential improvements
10.3760/cma.j.cn115396-20230517-00132
- VernacularTitle:胰瘘定义历史沿革与当前分级局限性和可能改进
- Author:
Chenghao LIU
1
;
Dianrong XIU
Author Information
1. 北京大学第三医院普通外科，北京 100191
- Keywords:
Postoperative complications;
Pancreaticoduodenectomy;
Amylases;
Pancreatic fistula;
Pancreaticojejunostomy;
Pancreatic digestive tract reconstruction;
Pancr
- From:
International Journal of Surgery
2023;50(6):361-365
- CountryChina
- Language:Chinese
-
Abstract:
Pancreatic fistula is one of the most important complications after pancreatic surgery. The International Study Group on Pancreatic Fistula proposed the definition and classification of postoperative pancreatic fistula (POPF) in 2005 firstly, which has promoted the development of pancreatic surgery research. And the International Study Group on Pancreatic Surgery modified the POPF standard in 2016 and paid more attention to clinical relevance. The POPF is often used to evaluate anastomotic methods. However, this grading version is based on clinical outcomes, which more represents the comprehensive treatment effect than reflects the quality of pancreaticojejunostomy. Using the current POPF grading criteria for the purpose of improving anastomosis methods is not very accurate, so an indicator that only reflects anastomosis′ quality is needed for the comparison of various surgical methods. To avoid the influence of non-reconstruction elements on the incidence and degree of POPF, this research team prefer the total drainage fluid amylase(DFA)or the duration of high DFA. And in this way, the comparation among different anastomotic operations could be specific and objective, which further helps to find out an ideal method for pancreatic digestive tract reconstruction.
