Research progress of hyperthermic intraperitoneal chemotherapy in the treatment of colorectal cancer
10.3760/cma.j.cn115396-20230419-00103
- VernacularTitle:腹腔热灌注化疗在结直肠癌治疗中的研究现状
- Author:
Fu LI
1
;
Chenyuan GUO
;
Bo HUANG
Author Information
1. 山西医科大学第五临床医学院，太原 030000
- Keywords:
Colorectal neoplasms;
Peritoneum;
Prognosis;
Hyperthermic intraperitoneal chemotherapy;
Cytoreduction surgical
- From:
International Journal of Surgery
2023;50(5):354-360
- CountryChina
- Language:Chinese
-
Abstract:
Colorectal cancer is a common digestive system malignant tumor in the world, its incidence and mortality rate is in the forefront, with the social progress and the change of diet structure, the incidence of colorectal cancer is gradually increasing, and there is a trend of younger age. Among them, peritoneal metastasis is the main cause of death in patients with colorectal cancer. Non-surgical treatment has been used in the past, but the prognosis is poor. How to treat and prevent peritoneal metastasis in colorectal cancer patients and improve the prognosis of such patients as much as possible is a question worth our in-depth study. The hyperthermic intraperitoneal chemotherapy provides a new direction for the treatment of colorectal cancer patients, usually combined with surgical treatment, and co-applied in the clinic as a new treatment model. This article reviews the treatment mode of hyperthermic intraperitoneal chemotherapy, the choice of drugs, and the progress of research in the treatment and prevention of peritoneal metastasis in colorectal cancer.
