Research progress on platelet-rich fibrin preparation and preservation technology
10.3760/cma.j.cn115396-20230213-00026
- VernacularTitle:富血小板纤维蛋白制备和保存技术研究进展
- Author:
Jingyuan SHI
1
;
Tonghan LI
;
Hong ZHAO
Author Information
1. 华中科技大学同济医学院附属同济医院创伤外科，武汉 430030
- Keywords:
Biocompatible materials;
Platelet-rich fibrin;
Centrifugation;
Freeze drying;
Wound healing
- From:
International Journal of Surgery
2023;50(3):212-216
- CountryChina
- Language:Chinese
-
Abstract:
Platelet-rich fibrin(PRF), a second-generation of platelet concentrate with stereo fibrin structure, leukocyte and platelets, can release various cytokines and growth factors to promote wound healing. PRF has been widely used in the treatment of various acute and chronic wounds in traumatic surgery, plastic surgery and stomatology. Chronic wounds are common in traumatic surgery, but conventional treatment is often ineffective. Accumulating evidences have confirmed that PRF has excellent therapeutic effect on chronic wounds. According to various methods such as different specimen, centrifugation, centrifuge tube material, and freeze-drying, the researchers tried to improve the efficiency of PRF. The progress of platelet-rich fibrin preparation technology and preservation technology are reviewed in this paper.
