A Case of Surgical Treatment of Nesidioblastosis with Hyperinsulinemic Hypoglycemia in an Adult.
- Author:
Bong Su KANG
1
;
Sung Il KANG
;
Hye Young KOO
;
Sung Bae LEE
;
Hye Yun KANG
;
Seok Won PARK
;
Chul Woon CHUNG
Author Information
1. Department of Surgery, College of Medicine Pochon CHA University, Sungnam, Korea. wehrwolf@cha.ac.kr
- Publication Type:Case Report
- Keywords:
Nesidioblastosis;
Hyperinsulinemia;
Hypoglycemia;
Surgery
- MeSH:
Adult;
Angiography;
Blood Glucose;
Calcium;
Endocrine Cells;
Head;
Humans;
Hyperinsulinism;
Hypoglycemia;
Insulinoma;
Nesidioblastosis;
Pancreas;
Unconscious (Psychology)
- From:Korean Journal of Hepato-Biliary-Pancreatic Surgery
2008;12(4):302-306
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Nesidioblastosis is a rare disorder, and it usually considered as a cause of neonatal hyperinsulinemic hypoglycemia. A 35 year-old-woman with hyperinsulinemic hypoglycemia was admitted in an unconscious condition. Abdominal CT, pancreas MRI and celiac angiography with an intra-arterial calcium stimulation test revealed a suspicious insulin-producing tumorous lesion in the head of pancreas. The patient underwent enucleation of the pancreas head tumor under the initial diagnosis of insulinoma. However, the tumor was confirmed histologically as nesidioblastosis that showed ductoendocrine proliferations and numerous small endocrine cell groups. Nesidioblastosis is classified into a focal type and a diffuse type, which are characterized by different clinical outcomes. The patient in our case showed a normal blood glucose level after operation, which is often the case for the focal type. Herein, we report this very rare case of adult nesiodioblastosis that was successfully treated by surgical resection.
