Application progress in synthetic and natural polymer materials for dural membrane repair
10.3760/cma.j.cn121382-20221228-00211
- VernacularTitle:合成高分子材料和天然高分子材料在硬脑膜修复中的应用进展
- Author:
Zhixuan YANG
1
;
Yuet-Wai LAM
;
Yuan ZHANG
;
Yongmei CHEN
;
Qiqing ZHANG
Author Information
1. 陕西科技大学，西安 710021
- Keywords:
Dura mater;
Synthetic polymer;
Natural polymer
- From:
International Journal of Biomedical Engineering
2023;46(2):156-162
- CountryChina
- Language:Chinese
-
Abstract:
The dura mater is a double-layer tough membrane tissue located between the surface of the brain and the inner surface of the skull that supports and protects the brain tissue. The phenomenon of dural defects caused by tumor resection, inflammation destruction, and craniotomies is becoming more common clinically. Therefore, the development of effective dural repair materials can not only reduce the leakage of cerebrospinal fluid and the occurrence of epilepsy complications but also promote the recovery of the dural defect to its normal physiological structure. With the continuous development of modern medicine, many biomaterials have been developed for dural defect repair. At present, the most promising and most researched biomaterials are synthetic polymer materials and natural polymer materials. Synthetic polymer materials have been extensively studied by domestic and foreign scholars due to their stable performance, low foreign body infection, and easy mass production advantages. Natural polymer materials are the most promising biomaterials because of their extensive sources, excellent biocompatibility, and biodegradability advantages. This article summarizes the research progress based on synthetic polymer materials and natural polymer materials in dural repair materials. In this review paper, the application progress of synthetic polymer materials and natural polymer materials in dural membrane repair was reviewed.
