Preparation of monodisperse microspheres by electrospray and their biomedical applications
10.3760/cma.j.cn121382-20221128-00115
- VernacularTitle:电喷雾法制备单分散微球及其生物医学应用
- Author:
Tianxia ZHAO
1
;
Ming MA
;
Yu ZHANG
Author Information
1. 东南大学生物科学与医学工程学院,生物电子学国家重点实验室,江苏省生物材料与器件重点实验室,南京 210096
- Keywords:
Electrospraying;
Microsphere;
Preparation;
Biomedical applications
- From:
International Journal of Biomedical Engineering
2023;46(1):88-94
- CountryChina
- Language:Chinese
-
Abstract:
Electrospray technology is a method to prepare microspheres by electrostatic force. Electrospray technology has the advantages of simple operation and mild reaction conditions. The polymer microspheres prepared by electrospray technology have uniform morphology and good monodispersity, which is a new and promising method. In this paper, the devices and principles of electrospray technology, the factors affecting the morphology and particle size of the prepared polymer microspheres by the electrospray process, and the types of polymer solutions commonly used in electrospray technology were described, and the applications of electrospray technology for drug delivery, loaded nanoparticles, cell therapy, and bioactive substance delivery were reviewed. It can be concluded that electrospray technology has a broad application prospect and potential application value.