Analysis of epidemiological characteristics and pathogen infection in children with diarrhea in Tianjin
10.3760/cma.j.cn121382-20220705-00503
- VernacularTitle:天津地区腹泻患儿病原体感染情况和流行病学特征分析
- Author:
Lu WANG
1
;
Wei WANG
;
Shuxiang LIN
;
Yulian FANG
;
Mengzhu HOU
;
Jinying WU
;
Yu ZHAO
Author Information
1. 天津市儿童医院天津市儿科研究所，天津 300134
- Keywords:
Children;
Diarrhea;
Pathogens;
Epidemiology
- From:
International Journal of Biomedical Engineering
2022;45(5):390-394
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To understand the pathogen infection and epidemiological characteristics of children with diarrhea in Tianjin.Methods:Stool samples from 1 466 children with diarrhea in Tianjin Children's Hospital from August 2017 to July 2018 were collected, and all samples were tested for five intestinal-related pathogens (norovirus, rotavirus, Clostridium difficile toxin, adenovirus, and astrovirus). Results:Among the 1 466 samples, 627 samples were positive for nucleic acid detection of intestinal pathogens, with a positive rate of 42.8%. The detection rate of norovirus was the highest (26.3%), followed by rotavirus (15.3%), Clostridium difficile toxin (4.6%), adenovirus (4.1%), and astrovirus (1.84%). The infection has obvious seasonality. The positive detection rates of the five pathogens were similar among children of different sexes, and only the positive detection rates of norovirus and rotavirus were statistically significant among different ages ( P<0.05). There were 110 cases of mixed infection, and the mixed infection of norovirus and rotavirus was the most common, with a total of 37 cases. Conclusions:The pathogen spectrum of infant infectious diarrhea in Tianjin is complex and diverse, and the main pathogens are norovirus and rotavirus.
