Magnetic resonance imaging evaluation of cerebral amyloid angiopathy
10.3760/cma.j.issn.1673-4165.2023.05.011
- VernacularTitle:脑淀粉样血管病的MRI评价
- Author:
Jun YANG
1
;
Zhaoying WU
;
Lili ZHANG
;
Yuzhong WANG
;
Xungang FENG
Author Information
1. 济宁医学院附属医院神经内科，济宁 272029
- Keywords:
Cerebral amyloid angiopathy;
Magnetic resonance imaging;
Diagnosis;
Differentiation
- From:
International Journal of Cerebrovascular Diseases
2023;31(5):378-383
- CountryChina
- Language:Chinese
-
Abstract:
Cerebral amyloid angiopathy (CAA) is a common cerebral small vessel disease, mainly caused by β-amyloid deposition on the small vessels less than 200 μm in diameter in cortex and leptomeninges. CAA is a major cause of spontaneous intracerebral hemorrhage in the elderly, especially lobar location. Early symptoms are insidious, and as the disease progress, they manifest as cerebral hemorrhage, cognitive decline, transient focal neurological episodes, cerebral infarction, epilepsy, headache, etc. MRI revealed that CAA is a disease in which bleeding and ischemia coexist, and even inflammation and immune responses are involved. MRI findings of CAA include cerebral hemorrhage, cerebral microbleeds, convexity subarachnoid hemorrhage and cortical superficial siderosis, cortical microinfarcts, CAA-associated inflammation, white matter hyperintensities, enlarged perivascular spaces, cerebral atrophy and lacune, etc. The same patient often has several of the above manifestations, and each manifestation has different specificity for the diagnosis of CAA. The rapid development of MRI technology has led to the improvement of the diagnostic level of CAA, and it is of great clinical significance to understand these imaging findings. This article reviews the MRI findings of sporadic CAA.
